(079) Early Results of Universal Cardiovascular Disease Risk Assessment in Young Men Presenting with ED and/or Low T

Abstract Introduction Erectile dysfunction (ED) and low testosterone (low T) are common men’s health issues, affecting ~40 million 4 men in the United States, respectively. 1 Typical risk factors for early ED include cardiometabolic that may be associated with increased premature CVD. Low T levels have also been strongly implicated as an independent factor CVD development progression. 2 Whether screening atherosclerotic disease younger such conditions identify potentially high-risk individuals initiation of preventive therapies is unknown. Objective To assess presence burden young and/or Methods Our study a prospective, longitudinal assessment cardiovascular all aged 18-55 presenting to high-volume center hypogonadal complaints serum TT <350ng/dL. Exclusion criteria included prior TRT, history, or history having seen cardiologist at any point past. All meeting these basic were automatically referred preventative cardiac assessment. Prior cardiology evaluation, patients had IIEF AUA questionnaire scores, STOPBANG scores obstructive sleep apnea (OSA) prediction, hormone profile (TT, E2, PRL, FSH, LH). lipid profile, EKG, Coronary Artery Calcium (CAC) score assessed by CT, carotid Doppler US, other studies (e.g. echocardiography) indicated. Results Of first 35 sent assessment, 15 (43%) mean age 40 years (range 23-50) completed aspects Overall, 7/15 (40%) CAC >0, including 2/7 (28%) years. Three >40 (38%) very high (87 138). Carotid US showed clinically significant plaque 2/15 (13%). Conclusions initial data suggest undiagnosed not uncommon T. Typically non-zero slightly more often, finding 63% our cohort much higher than general male population. The severe nearly 40% 40-50 even worrisome. While results, they seem noteworthy based on scoring ED/low issues. As prospective collection continues, we anticipate information gathered will strengthen tie between We hope data, generated simple, universal referral pathway, help serve basis future guideline-mandated evaluation this at-risk patient Disclosure No